Dr. Mohammad Karim



Professor - Organic Chemistry                     Chair, Department of Chemistry

Contact Information:  Phone: 615-963-5344 Fax: 615-963-5326 Email: mkarim@tnstate.edu


  Research Group


Arifuzzaman-Currently pursuing PhD at Iowa Sate University, Ames, IA

Zinia Jaman-Crrently pursuing PhD at Purdue University, Lafayette, IN

Anisur Rahman-Currently pursuing PhD at University of South Carolina, Columbia, SC.

Rejaul Hoq

Md. Razzak


Areas Of Interest

Synthetic organic chemistry, development of new synthetic strategy, natural product synthesis, synthesis of anticancer and anti-AIDS agents.

       1.          Synthesis of Schiff’s Bases

       2.          Synthesis of Curcumol and Related Natural products

       3.          Synthesis of Cembranoid Diterpenes


1] Synthesis of Schiff bases from 2,2'-dipyridyl-5,5'-dialdehyde with thiocarbazates. Md. Rejaul Hoq, Mohammad R. Karim, Aminul H.Mirza, Korsi Dumenyo. International Journal of Organic Chemistry, 2015, 5, 29-36.

2] Synthesis of Loratadine and some of it's amide derivatives as cytotoxic agents. Lipiar Khan Mohammad Osman Goni, Nahida Akter, Md. Rabiul Islam, Anisur Rahman, Mohammad Karim. International Journal of Medicinal Chemistry & Analysis, 2015, vol 5, issue 2, pp 68-73.

3] Zn(II) Catalyzed Efficient Synthesis of 1,3,4-Oxadiazole and 1,3,4-Thiadiazole. Md. A. Rahman, Mohammad R. Karim **, Md. Arifuzzaman, Tasneem A. Siddiquee*, Aminul H. Mirza. Tetrahedron Letters, 2014, 55, 3267-73.

4] Synthesis, spectroscopy and X-ray crystal structures of some zinc(II) and cadmium(II) complexes of the 2-pyridinecarboxaldehyde Schiff bases of S-methyl- and S-benzyldithiocarbazates. Aminul Huq Mirza, Malai Haniti S.A. Hamid, Sazwani Aripin, Mohammad Rezaul Karim, Md. Arifuzzaman, Mohammad Akbar Ali, Paul V. Bernhardt. Polyhedron, 2014, 74, 16-23.

5] Antibacterial activities of new Schiff bases and intermediate Silyl compounds sythesized from 5-substituted-1,10-phenanthroline-2,9-dialdehyde. Zinia Jaman, Mohammad R. Karim, Korsi Dumenyo, Aminul H. Mirza. Advances in Microbilogy, 2014, 4, 1140-1153.

6] Synthesis and structure of dimeric Copper (I) complex from bis[(2,2’)-Dimethyl 2,2’-(1,10- Phenanthroline 2,9-diyl)bis (methan-1-yl-1- ylidene)-bis(hydrazinecarbodithioate)].  Md. Arifuzzaman*, Tasneem A. Siddiquee*, Mohammad R. Karim**, Aminul H. Mirza, Mohamad A. Ali, Crystal Structure: Theory and Applications (CSTA), 2013, 2, 159-166.

7] Antibacterial Study of Schiff Bases derived from 1,10-Phenanthroline-2,9-dialdehyde with Sulfur-containing Amines. Md. Arifuzzaman*, Korsi Dumenyo, Mohammad R. Karim**, Aminul H. Mirza, J of Microbiology, To be submitted, 2013

8] Synthesis of 5-Substituted 2, 9-Dimethyl-1,10-Phenanthroline Dialdehydes and Their Schiff bases with Sulfur-containing Amines. Zinia Jaman*, Mohammad R. Karim**, Tasneem A. Siddiquee*, Aminul H. Mirza, Mohamad A. Ali. International Journal of Organic Chemistry, 2013, Accepted

9] Synthesis and Characterization of New Schiff bases formed by Condensation of 2,9-Phenathroline-1,10-dialdehyde with Sulfur-containing Amines; Md. Arifuzzaman*, Mohammad R. Karim**, Tasneem A. Siddiquee*, Aminul H. Mirza, Mohamad A. Ali, International Journal of Organic Chemistry, 2013, 3(1), 81-86

10]  Template synthesis and X-ray structural characterization of nickel(II) and zinc(II) complexes of tetradentate SNNS ligands formed by condensation of phthalaldehyde with S-methyldithiocarbazate and 4N-methyl-3-thiosemicarbazide Mohammad Akbar Ali a , , Aminul Huq Mirza a , Chan Chin Mei a , Paul V. Bernhardtb , Mohammad Rezaul Karim c . Polyhedron, 2013, 49, 277-283.

11]  Self-assembling dicopper(II) complexes of di-2-pyridyl ketone Schiff base ligands derived from alkyldithiocarbazates; Mohammad Akbar Ali*a, Aminul H. Mirzaa , Ray J. Butcherb , Paul V. Bernhardtc, Mohammad Rezaul Karim d ; Polyhedron 2011, 30 (9), 1478-1485.

12]  “2,9-Bis(1,3-benzothiazol-2-yl)-1,10-phenanthroline dichloromethane disolvate” Jesmin Akther, Sergey Lindeman and Mohammad R. Karim*; Acta Cryst 2008, E64, 01836

13]  "Hemicholinium - 3 Mustard Reveals Two Populations of Choline Cotransporters with Different Properties." M.T.Ivy, R.F.Newkirk, M.R. Karim, C.M.P.Mtshali and J.G.Townsel, Neuroscience, 2001, 102(4), 969-978.

14]  "Revelation of Silent Choline Cotransporters" M.D. Kemp, R.F. Newkirk, M.T. Ivy, M.R. Karim and J.G. Townsel; Society for Neuroscience Conference, Los Angeles, California, , Nov 7-12, 1998.

15] "Hemicholinium Mustard Reveals a Constitutive Cycling Choline Cotransporter" R.F. Newkirk, M.T. Ivy, M.R. Karim, and J.G. Townsel; Society for Neuroscience Conference, Los Angeles, California, , Nov 7-12, 1998.

16]  "A Hemicholinium-3 Mustard Reveals Two Populations of Choline Cotransporters with Different Properties” Michael T. Ivy, Mohammad R. Karim, Robert F. Newkirk, Byron D. Ford and James G. Townsel; Neuroscience Abstracts, 1998, Vol 23(2), p1239.

17]  "Preparation and Nucleic-Acid Binding of Ellipticine Derivatives." Kennedy, G. D., Krishnan, G., Karim, M., and Harden, D. (1997). Heterocyclic Communications, 2, 125-128.

18]  "Pulping Catalyst From Lignin (5). Nitrogen Dioxide Oxidation of Lignin Models to Benzoquinones", Dimmel, D. R.; Karim, M.R.; Savidakis, M.C; Bozell, J.J.; J. Wood Chem. Technol., 1996, 16, 169.

19]  Kennedy, G. D., Krishnan, G., Karim, M., and Harden, D. (1996). Preparation and Nucleic-Acid Binding of Ellipticine Derivatives. Heterocyclic Communications, 2, 125-128.

20]  “Effects of Electron Donating Groups on the Ene Donor in Intramolecular Ene Reaction”, M.R. Karim, Leon Smith, at 211th National Meeting of the American Chemical Society, March 24-28, 1996, in New Orleans, Louisiana (ORGN. 42)

21]  "Degradation of Dibenzodioxin during Chlorine Dioxide Bleaching of Kraft Pulp", Alison K. Daube, Mohammad R. Karim, Donald R. Dimmel, Thomas J. McDonough, Sujit Banerjee; Environ. Sci. Technol. 1992, 22, 1324

22]  "A new and Efficient Approach to Macrocyclic Ketolactones", Karim, M.R.; Sampson, P.* J. Org. Chem., 1990, 55, 598.

Book Review:

             1.        Fundamentals of Chemistry, Chapters 5 and 9, 3rd edition by David Goldberg, McGraw-Hill Publisher, January 2001.

             2.        Modern Organic Synthesis: An Introduction by Michael Nantz and George Zweifel W.H. Freeman and Company, Publishers. May, 2005


  •       Department of Education Award, 1997
  •       Special recognition by MOHONA Cultural group of Atlanta, 1996
  •        Kent State University Fellowship (1989)
  •         Waldo-Semon Graduate Research Award by KSU and B.F. Goodrich.               
  •         American Chemical Society Award (1988)
  •         Dissertation award (1988) at Kent State University
  •         Teaching Fellowship (1985-89) in the Department of Chemistry, Kent State University, Kent, Ohio.               


Ph.D.    Kent State University (Org. Chemistry), Kent, Ohio, 1989    

M.S.      Jahangirnagar University (Org. Chemistry), Dhaka, Bangladesh, 1980

B.S.      Jahangirnagar University (Chemistry), Dhaka, Bangladesh.


  • ·General Chemistry
  • ·Organic Chemistry
  • ·Spectroscopic methods
  • ·Advanced Organic Chemistry
  • ·Special Topics Organic – Retrosynthetic Analysis
  • ·Scientific Communications
  • ·Organic Chemistry Survey

Detailed CV

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