Rejaul's Research Focus
Synthesis of Schiff Bases from 2,2'-Bipyridyl-4,4' & 5,5'-Dialdehyde with Thiocarbazates
Design and synthesis of organic chelating agents containing nitrogen and sulfur as donor atoms and their metal complexes is an interesting field of research for their different types of activities. The bi-dentate N,N chelating agent such as 2,2-Bipyridal has been playing a vital role in synthetic and medicinal chemistry. 2,2 - Bipyridal has been used to preparing many mixed-ligand complexes. Different ligand complexes prepared from 2,2 - Bipyridyl are used in different areas such as molecular catalysis, solar energy conversion, calorimetric analysis, herbicides, molecular recognition, self-assembly, antineoplastic agents, and nucleic acid probes. Another important property of these type of compounds are the triplet state photosensitizing character of bipyridyl nucleus, which is shown in metal complexes. It is also found that compounds containing O,S,N atoms have received considerable attention because of their pharmacological studies like anticancer, antibacterial, and antitumour activities. Therefore, it has been decided to synthesize Schiff bases derived from 2,2’-bipyridyl-5,5’-dicarbaldehyde compounds with O,S,N-containing amines and study their antibacterial properties. Several new Schiff bases have been synthesized and fully characterized by spectral data. This paper presents the synthesis and characterization of newly designed Schiff bases.
1] "Synthesis of Schiff bases from 2,2'-dipyridyl-5,5'-dialdehyde with thiocarbazates". Md. Rejaul Hoq, Mohammad R. Karim, Aminul H.Mirza, Korsi Dumenyo. International Journal of Organic Chemistry, 2015, 5, 29-36.
2] Synthesis of Schiff bases from 2,2'-dipyridyl-4,4'-dialdehyde with thiocarbazates. Md. Rejaul Hoq, Mohammad R. Karim, Aminul H.Mirza, Korsi Dumenyo. International Journal of Organic Chemistry, 2015 (manuscript in preparation).