Dr. Elbert Lewis Myles, Jr.
Agriculture, Human & Natural Sciences
Location: Harned Hall, Room 213; Lab, 302/304
Principles of Genetics, Molecular Genetics, Advance
Genetics, Environmental Genetics, Plant Physiology, Cell Biology, and Molecular
Genetics and Molecular Biology.
are a number of molecules/secondary compounds derived from plants, and bacteria
isolated as anticancer and antimicrobial agents. Many of these compounds are
thought to have anti-tumor and/or bacterial activity, however, they are lacking
experimental evidence to support these concepts. We believe there is a greater possibility of
finding biological activity among plants with ethno-medicinal value rather than
from plants that are randomly selected. Therefore, based on this rationale the
major aims underlying our study are to identify bioactive plants based
primarily on their ethnomedicinal usage and rapidly conduct efficient and
accurate bioassay screening methods. With respect to anticancer/antibacteria
drug screening, for cytotoxicity and cell viability assays would provide
sufficient preliminary data to facilitate the identification of such plants
Peer-reviewed Publications (in chronological
W.C., H.N. Nagler, J.S. Fang, E.L. Myles
and G.M. Jagiello. 1988. Infertility in
a patient with abnormal spermatogenesis and in utero DES exposure.
International Journal of Fertility
E. L. Myles, Jr. and J.E.
Endrizzi. 1989. Aneuploids induced by deficiencies of
chromosome 9 and analysis of the time of nondisjunction in cotton. Genome.
E. Lewis Myles, Brenda Jordan,
Clifton Randell, Crystal Barbee, Deborah Long, Sarabjit Bhatti and Roger Sauve.
2000. Innovative Use Of Purple Cone
Flower (Echinacea) As An Anti-Cancer Source, Proceedings of the Southern
Nursery Association. Vol 45 (3) 258-260
Long, Mary, Cherry, Sara Bhatti, RogerSuave,
E. Lewis Myles. 2001 HPLC Analysis of active constituents in three species
of hypericum. Proceedings of the Southern Nursery Association. Vol. 46 (2)
M.T. Mmbaga, F.J. Avila, E.F. Howard,
and E.L. Myles. 2006. Accumulation
of a Protein Associated with Plant Defense in Powdery Mildew Resistant Dogwood (Cornus florida) Journal Of Environmental Horticulture Volume
24, Issue 2
Edwards - P. Armstrong - G.d. Goode - C. Mtshali - S. Williams - E.L. Myles - B. Washington -2007. 6.
Cross-Talking Between Calcium And Histamine In The Expression Of Mapks In
Hypertensive Vascular Smooth Muscle Cells. Cellular and Molecular Biology Vol
Shaw - Q. Cai - C. Mtshali - E.L. Myles
- B. Washington. 2007. Heterogeneity Of Histamine H3 Receptor Genomic
Expression In The Cerebral Cortex Of Spontaneously Hypertensive Rat Cellular and Molecular Biology Vol 53 (4): -
Johnson - G.d. Goode - C. Mtshali - E.L.
Myles - B. Washington. 2007. Protein
Kinase C- Α/ßii, Δ, And Ζ/Λ Involvement In Ethanol-Induced Mapk Expression In
Vascular Smooth Muscle CellsCellular and Molecular Biology, Vol 53 (4): 38-44
O. Fadeyi a, Saudat T. Adamson b, E. Lewis Myles
b, Cosmas O. Okoro a,2008. a
Department of Chemistry, b Department of Biological Sciences,
Bioorganic & Medicinal Chemistry Letters 18 (2008) 4172–4176
T, Butler, J, Arino de la Rubia, L., Myles,
E. L., Bradford, K, Kirven-Brooks, M., Deballos, R. M., Taylor, L, Bell, B
and Coulter, G. 2009 The NASA
Astrobiology Institute-Minority Institution Research Support Program:
Strengthening the Astrobiology Community. Bioastronomy: Molecules, Microbes and
Extraterrestrial Life. ASP conference
Series Vol. 420, p477-484,
Oluropo C. Agbaje a, Olugbeminiyi O. Fadeyi a, S.
Adamson Fadeyi b, E. Lewis.
, Cosmas O. Okoro a,* 2010; Synthesis and in
vitro cytotoxicity evaluation of some fluorinated hexahydropyrimidine
derivatives; a Department of Chemistry, Tennessee State University, 3500 John
A. Merritt Blvd., Nashville, TN 37209-1561, USA. b Department of Biological
Sciences, Tennessee State University, 3500 John A. Merritt Blvd., Nashville, TN
37209-1561, USA Bioorganic & Medicinal Chemistry Letters 21 (2011) 989–992
Chair (Multi year) Botany Section Tennessee Academy of
Coordinator (Multi-year) Collegiate Division Tennessee
Academy of Science
Reviewed Grant Application National Science Foundation
review: iGenetics: A Molecular Approach, “Peter J. Russell, &
University wide Annual Research Committee, Chair of University wide Annual
Research Committee (4 yrs); Chair of Curriculum Committee, Serve on Assessment
and Retention Committee, Member of the Graduate Faculty, Provide research
training for Graduate and Undergraduate Students.
State University, Nashville, TN, Biological Sciences B.S. 1974
State University, Nashville, TN, Biological Sciences M.S. 1976
of Arizona, Tucson, Arizona, Committee of Genetics Ph.D. 1985
Fellow, Columbia University Med School, N. Y. 1984 – 1986
Associate for Cooperative Agricultural Research Prog. 1986 - 1989
Date Joined University Staff: 1986
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Resume of Dr. Myles