Dr. Michael T. Ivy


Michael Ivy picture











Department of Biological Sciences
College of Life & Physical Sciences


Contact Information:

Office Location: 316 Harned Hall
Telephone: 615-963-7796
FAX: 615-963-5747
Email: mivy@tnstate.edu

Research Areas:

Neuroscience, Cholinergic nervous system, Diabetes, Nephrology, protein trafficking, etc.



Refereed journal Articles 19
Research abstracts 36
Conference Presentations and Invited Lectures 38


Publications (Peer-Reviewed):

Amara, S., Lopez, K., Banan, B., Brown, S-K., Whalen, M., Myles, E., Ivy, M.T. , Johnson, T., Schey, K.L., and Tiriveedhi, V.; 2015; Synergistic effect of pro-inflammatory TNFa and IL-17 in periostin mediated collagen deposition:  Potential role in liver fibrosis.  Molec. Immunol.  64:  26-35.

Fidler, A.L., Vanacore, R.M., Chetyrkin, S.V., Pedchenko, V.K., Bhave, G., Yin, V.P., Stothers, C.L., Rose, K.L., McDonald, W.H., Clark, T.A., Borza, D-B., Steele, R.E., Ivy, M.T., The Apirnauts, Hudson, J.K., and Hudson, B.G.; 2014; A unique covalent bond in basement membrane is a primordial innovation for tissue evolution.  PNAS ID: 1318499111 111(1):331-336.

Bohannon-Stewart, A., Kelley, G., Kimathi, B., Subramanya, S.H.K.V., Donkor, J., Darris, C., Tyus, J., Payne, A., Byers, S., Hui, D., Nahashon, S., Chen, F-C, Ivy, M., and Wang, X, 2014; Expression of Potential Regulatory Genes in Abdominal Adipose Tissue of Broiler Chickens during Early Development, Gen. Res. Int. 2014: ID 318304.

Ruggiero, A.M., Wright, J., Ferguson, S.M., Lewis, M., Emerson, K.S., Iwamoto, H., Ivy, M.T., Holmstrand, E.C., Ennis, E.A., Weaver, C.D. and Blakely, R.D.; 2012; Nonoisotopic assay for the presynapptic choline transporter reveals capacity for allosteric modulation of choline uptake; ACS Chemical Neurosci. 3:767-781.

Ivy, M.T., Newkirk, R.F. and Townsel, J.G.; 2010; A novel choline cotransporter sequestration compartment in cholinergic neurons revealed by selective endosomal ablation; J. Neurochem. 112(5):1295-1304.

Cao, Z., Wang, Y., McAdory, B.S., Kemp, M.D., Ivy, M.T., Newkirk, R.F. and Townsel, J.G.; 2006; Identification and characterization of syntaxin 1 antisense variants in Limulus polyphemus; Cell. Mol. Neurobiol. 26(1):53-66.

Wang, Y., Cao, Z., Xu, W., Kemp, M.D., McAdory, B.S., Newkirk, R.F., Ivy, M.T. and Townsel, J.G.; 2004; Cloning and partial characterization of four plasmalemmal-associated syntaxin isoforms in Limulus; Gene 326:189-199.

Wang, Y., Cao, Z., Newkirk, R.F., Ivy, M.T. and Townsel, J.G.; 2001; Molecular cloning of a cDNA for a putative choline co-transporter from Limulus CNS; Gene 268:123-131.

Ivy, M.T., Newkirk, R.F., Karim, M.R., Mtshali, C.M.P. and Townsel, J.G.; 2001; Hemicholinium-3 mustard reveals two populations of cycling choline cotransporters in Limulus; Neurosci. 102(4):969-978.

Wang, Y., Cao, Z., Reid, E.A., Newkirk, R.F., Ivy, M.T. and Townsel, J.G.; 2000; The use of competitive PCR mimic to evaluate a Limulus lambda phage genomic DNA library; Cell. Mol. Neurobiol. 20(4):509-520.

Ford, B.D., Ivy, M.T., Mtshali, C.P. and Townsel, J.G.; 1999; The involvement of protein kinase C in the regulation of choline cotransport in Limulus; Comp. Biochem. Physiol. 123A:255-261.

Santiago, L.R., Ivy, M.T., Erickson, L.C. and Hanin, I.; 1995; AF64A-Induced cytotoxicity and changes in choline acetyltransferase activity in the LAN-2 Neuroblastoma cell line are modulated by choline and hemicholinium3; J. Neurosci. Methods 61:185-190.

Ivy, M.T. and Townsel, J.G.; 1989; A Vinblastine sensitive high affinity choline uptake system; Comp. Biochem. Physiol. 92C(1):81-88.

Carroll, P.T. and Ivy, M.T.; 1988; Effect of 2-(4-Phenylpiperidino)cyclohexanol (AH 5183) on the veratridine-induced increase in acetylcholine synthesis by rat hippocampal tissue; J. Neurochem. 51(3):808-819.

Ivy, M.T. and Carroll, P.T.; 1988; Evidence to suggest that the spontaneous release of acetylcholine from rat hippocampal tissue is carrier-mediated; Neurochem. Res. 13(4):325-328.

Ivy, M.T. and Townsel, J.G.; 1987; A comparative study of high affinity choline uptake and choline utilization in cholinergic and non-cholinergic tissues; Comp. Biochem. Physiol. 86C:111-120.

Ivy, M.T. and Townsel, J.G.; 1987; Biochemical evidence for cholinergic involvement in the Limulus Brain; Comp. Biochem. Physiol. 86C:103-110.

Ivy, M.T., Sukumar, R. and Townsel, J.G.; 1985; The characterization of a sodium-dependent high affinity choline uptake system unassociated with acetylcholine biosynthesis; Comp. Biochem. Physiol. 81C:351-357.

Sukumar, R., Ivy, M.T. and Townsel, J.G.; 1983; The distribution of cholinergic components in a marine arthropod; Comp. Biochem. Physiol. 74C:201-209.



BIO 4220-Endocrinology

BIO 4221-Endocrinology Laboratory

BIO 3200-Comparative Physiology

BIO 3201-Comparative Physiology Laboratory

BIO 4280-Pathophysiology

BIO 4281-Pathophysiology Laboratory

BIO 2220-Human Anatomy & Physiology II

BIO 2210-Human Anatomy & Physiology I

BIO 8110-Dissertation Research

BIO 7320-Neurophysiology

BIO 7170-Topics in Molecular Genetics

BIO 6100-Frontiers in Molecular Science

BIO 6110-Individual Research – Biology

BIO 5140-Special Problems I


Society for Neuroscience, Public Education and Communications Committee member, 2007-2010

Society for Neuroscience, Committee on Diversity in Neuroscience (C-DIN) member, 2006-2009

FASEB Summer Research Conference, Oral and Poster presenter at the New Perspectives in Transport Biology meeting, Saxtons River, VT, July 23-28, 2005

National Science Foundation (NSF), Minority Research Center of Excellence (MRCE) in Cell and Molecular Biology Summer Research Program for Faculty, MRCE Faculty Summer Research Program Award at Meharry Medical College, Dept. of Anatomy & Physiology, 1995

Minority Travel Award for Annual Meeting of the American College of Neuropsychopharmacology in San Juan, Puerto Rico, from the American College of Neuropsychopharmacology, December 10-14, 1990

Tarbox Postdoctoral Fellowship, for the Tarbox Parkinson’s Disease Institute of the Texas Tech University School of Medicine, Lubbock, Texas, August 1986-August 1988

Internal Research Grant, from the University of Illinois at Chicago, Biomedical Research Support Grant Program-Minority Research Support Fund, July 1984-June, 1985

Travel Fellowship for Minority Neuroscientists to the Society for Neuroscience 12th Annual Meeting in Minneapolis, Minnesota, from the Society for Neuroscience, Subcommittee on Minority Affairs, October 31-November 5, 1982

Graduate Student Research Award from the University of Illinois at Chicago, Graduate Col Dean’s Fund, April-Aug., 1982



B.A. – Southern Illinois University-Carbondale
Ph.D. – University of Illinois - Chicago


Date joined faculty:  1997


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