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Tennessee State University

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BSE: A Food Safety Issue

Fur-Chi Chen

Cooperative Agricultural Research Program Seminar Series
Tennessee State University, Nashville, TN
September 4, 2002

Bovine Spongiform Encephalopathy (BSE), commonly referred to as “Mad Cow Disease,” is a transmissible, slowly progressive, degenerative, fatal disease affecting the central nervous system of adult cattle. BSE belongs to the family of diseases known as the transmissible spongiform encephalopathies (TSEs). Other TSEs include scrapie in sheep and goats, transmissible mink encephalopathy, feline spongiform encephalopathy, chronic wasting disease in deer and elk, and Creutzfeldt-Jakob Disease (CJD) in humans. The agent that causes BSE and other TSEs has yet to be fully characterized.

BSE was first diagnosed in 1986 in the United Kingdom and since then has been confirmed in many other European countries and, most recently, in Japan. The disease is most likely spread by feeding rendered parts of cattle infected with BSE to other cattle in the form of meat and bone meal.  Scientific and epidemiological studies have linked variant Creutzfeldt-Jakob Disease (vCJD), a chronic and fatal neurodegenerative disease that affects humans, to the consumption of beef products contaminated with the BSE agent. In March 1996, the United Kingdom announced the first cases of this disease and linked it to BSE. By May 2000, 61 people in the United Kingdom, Ireland, and France had died from it, and the number and rate of new cases is increasing.

Neither vCJD nor BSE has been detected in the U.S. Since 1989, USDA has put in place a number of increasingly stringent safeguards to prevent BSE from entering the country. Imports of live ruminant animals and ruminant products from countries where BSE has been found or is suspected have been banned. As a precautionary measure, the FDA has also instituted a mammalian-to-ruminant feed ban under which materials processed from the slaughter of cattle, sheep and other animals cannot be used as feed for ruminant animals.

Given the actions already taken by USDA and FDA, the results of the risk assessment conducted by Harvard University show that BSE is extremely unlikely to become established in the U.S. If BSE should enter the U.S., the assessment indicates that most probably, only a small amount of potentially dangerous tissues would reach the human food supply. BSE agent is highly stable and resistant to enzyme degradation, freezing, drying and normal cooking temperatures, including pasteurization and sterilization, such as thermal processing of canned products. Therefore, it is urged that additional measures should be considered to minimize human exposure to BSE agents through products containing ingredients of bovine origin, such as some pharmaceuticals, gelatin, and beef stocks, extracts, and flavorings.

 

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