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Dr. Cosmas Okoro
Cosmas O. Okoro
Professor of Chemistry
College of Agriculture, Human & Natural Sciences
Contact Information:
Office Location: Boswell Sc. Complex Rm 004B
Telephone: 615-963-5325
FAX: 615-963-5326
Email: cokoro@tnstate.edu
Research Areas:
Synthetic Organic & Medicinal Chemistry
Computational Chemistry & Molecular Modeling
Publications/Citations
Refereed Journal Articles: 16
Journal Citations: 6
Research Abstracts: 15
Conference Presentations: 15
Most Recent Publications:
1. Gary L. Grunewald, Jian Lu, Kevin R. Criscione and Cosmas O. Okoro, Inhibitors of phenylethanolamine N-methyltransferase devoid of α2 –adrenoceptor affinity. Bioorganic & Medicinal Chemistry Letters 15 (2005) 5319-5323.
2. Cosmas O. Okoro, Olugbeminiyi O. Fadeyi, Patrice L. Jackson, Rhonda L. Richmond, and Takeisha Farmer, Synthesis of fluorinated cyclic s-trans vinylogous acid and amide ester derivatives. Tetrahedron Letters 47 (2006) 7451-7454.
3. Olugbeminiyi O. Fadeyi, and Cosmas O. Okoro, “Synthesis and reactions of Fluorinated Cyclic s-Trans Vinylogous acids and Amides: Palladium-catalyzed coupling of fluorinated cyclic s-trans enaminone with aryl and heteroaromatic halides”. Journal of the Tennessee Academy of Science, Vol 81, No. 3-4, page 88 (2006).
4. Fadeyi, Olugbeminiyi O.; Wash, Kendra; Okoro, Cosmas O.. Synthesis of fluorinated dihydropyrazolo-pyrimidine
derivatives as potential biologically active compounds. Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007 (2007), MEDI-408. CODEN: 69JAUY AN 2007:295837 CAPLUS
5. Olugbeminiyi O. Fadeyi, Cosmas O. Okoro. Synthesis of 5-(trifluoromethyl)cyclohexane-1,3-dione and 3-amino-5-(trifluoromethyl)cyclohex-2-en-1-one: new trifluoromethylbuilding block. Tetrahedron Lett. 49 (2008) 4725-4727.
6. Olugbeminiyi O. Fadeyi, Saudat T. Adamson, E. Lewis Myles, Cosmas O. Okoro. Novel fluorinated acridone derivatives. Part 1: Synthesis and evaluation as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters 18 (2008) 4172-4176.
7. Oluropo C. Agbaje, Olugbeminiyi O. Fadeyi, S. Adamson Fadeyi, Lewis E. Myles, Cosmas O. Okoro. Synthesis and in vitro cytotoxicity of some fluorinated hexahydropyrimidine derivatives. Bioorganic & Medicinal Chemistry Letters 21 (2011) 989-992.
8. Ogunwale, Mumiye A.; Okoro, Cosmas C. Synthesis of novel trifluoromethylated hexahydroquinoline derivatives as potential calcium channel modulators. Abstracts of Papers, 241st ACS National Meeting & Exposition, Anaheim, CA, United States, March 27-31, 2011 (2011), MEDI-142. CODEN: 69NZUR. AN 2011:338179 CAPLUS (Copyright © 2011 ACS on SciFinder ®
9. Mumini, Hadijatu; Okoro, Cosmas. Synthesis and antitumor activity evaluation of some trifluoromethylated indolones. Abstracts of Papers, 241st ACS National Meeting & Exposition, Anaheim, CA, United States, March 27-31, 2011 (2011), ORGN-735. CODEN: 69NZUR. AN 2011:339200 CAPLUS (Copyright ©2011 ACS on SciFinder ®
10. Cosmas O. Okoro, Tasneem Siddiquee, and Olugbeminiyi O. Fadeyi. 5,7-Dibromo-3-trifluoromethyl-3,4-dihydroacridin-1 (2H)-one.Acta Cryst. (2011). E67, o2052
Teaching:
CHEM 1100/CHEM 1101 – Fundamental of Organic & Biochemistry Lecture/Lab
CHEM 2010/2011 - Organic Chemistry I Lecture/Lab
CHEM 2020/2021 – Organic Chemistry II Lecture/Lab
CHEM 4100 – Scientific Communication
CHEM 4420 – Introduction to Medicinal Chemistry
CHEM 5210 – Advanced Organic Chemistry
Professional Affiliations:
American Chemical Society Division of medicinal Chemistry
Sigma Xi Scientific Research Society
Phi Lambda Upsilon Honorary Chemical Society
Beta Kappa Chi Scientific Honor SocietyAmerican Association of Pharmaceutical Scientists
Tennessee Cancer Coalition
International Who’s Who of Professionals
Chair, Nashville section of the American Chemical Society
Tennessee Academy of Sciences
Education
B.S. Chemistry (1981) –North Carolina Central University, Durham, N. C.
M.S. Organic Chemistry (1986) –North Carolina Central University, Durham, N. C.
Ph.D. Organic Chemistry (1993) –Howard University, Washington, DC
Postdoctoral Research Associate, (1993-1995), Florida A & M College of Pharmacy and Pharmaceutical Sciences
NIH Fellow in Medicinal chemistry (1999-2000), University of Kansas, Lawrence, KS
webpage contact:
Chemistry