Dr. William Boadi

student on campus  Department of Chemistry

TSU, Rm 209, 3500 John A. Merritt Blvd.

Nashville, TN 37209

Tel: (615) 963-5330

Email: wboadi@tnstate.edu

 

Objective

To continue to participate in teaching, research and scholarly activity to the best use of my unique multi-disciplinary scientific skills.

 

Education & Training

Post.doc. 10/97- 99 Toxicology, Massachusetts Institute of Technology, Cambridge, MA, Method Development, Oxidative DNA Damage, Drug Metab.

D.Sc. 10/88-11/91 Toxicology, Technion-IIT, Haifa, Israel - Food Engineering & Biotechnology

M.Sc. 10/85-09/88 Toxicology, Technion-IIT, Haifa, Israel - Food Engineering & Biotechnology

B.Sc. 01/79-06/82 University of Science & Technology, Dept. of Agric., Kumasi, Ghana

 

Strengths

Advanced skills in Biochemical and Molecular Biology techniques

Strong Analytical, Bioanalytical and Biochemical background

Experience in GMP/GLP practices, familiar with ICH guidelines

Self-motivated, enthusiastic, strong communication and leadership skills

 

Experience

07/2010-Date Professor (Tenured) Department of Chemistry, Tennessee State University (TSU), Nashville, Tennessee

Our current studies are focused on the mechanisms of novel compounds such as acridones and their derivatives as cancer preventive agents and on their abilities in modulating glutathione (GSH) levels following the exposure to the said compounds.

08/2004-07/2010 Associate Professor (Tenured) Department of Chemistry, Tennessee State University (TSU), Nashville, Tennessee

Our previous and published information from this laboratory have shown that plant flavonoids (namely, quercetin and genistein) do inhibit lipid peroxides in methyl linolenate and in human progenitor mononuclear (U937) cells. In the case of the U937 cells we observed a correlation between reduced lipid peroxides and the increased glutathione (GSH) levels supporting our earlier hypothesis that the reduced lipid peroxides may be due to the increased GSH levels. Our studies are focused on the mechanisms involving the up regulation of GSH levels following the exposure to these compounds.

06/2004-06/2009 Visiting Professor Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee

VEGF released from tumor cells stimulate angiogenesis from surrounding vessels. New vessels are leaky, resulting in the extravasation of serum proteins. This leads to the formation of a fibrin matrix that supports endothelial cell growth and migration. Current

studies involves both angiogenic (VEGF) and angiostatic factors (PEDF, TIMP-1 & 2, Throbonspondin etc.) on neovascularization in poked and non-poked rats. Fractionation of angiogenic and angiostatic proteins by cation exchange chromatography and how the fractionated proteins affect the proliferation of endothelial cells. Current findings indicate that proteins from vitreous of poked rats significantly inhibit human endothelial cells proliferation. The ultimate aim of this work is to find other therapeutic agents which can stimulate the release of angiostatic factors to mimic the effect seen in poked rats (i.e., increased release of angiostatic proteins) to prevent angiogenesis as evidenced in diabetics.

06/2000-06/2007 Consultant, Department of Medical Education, Meharry Medical College, Nashville, Tennessee

Volunteered & instructed new post baccalaureate students in Inorganic and Organic Chemistry and to prepare them for their respective MCAT & DAT exams.

08/99-06/2004 Assistant Professor Department of Chemistry, Tennessee State University (TSU), Nashville, Tennessee

Studies on the antioxidative effects of flavonoids on heavy metal oxidation (i.e., Cd2+, Ni2+ etc.) of DNA and their contribution to the mutagenic burden of the cell. Other research areas involve the identification of new products formed from endogenous oxidation of deoxyribose by heavy metals (e.g., abstraction of hydrogen from 5’ of ribose) and how these products affect endogenous DNA adduct formation.

10/97-09/99 Postdoctoral Associate Division of Bioengineering & Environmental Health, Massachusetts Institute of Technology (M.I.T), Cambridge, MA

Researched mechanisms by which products of certain amino acid metabolism under certain disease conditions (e.g., Tyrosinemia) damage DNA. The level of Peroxynitrite damage on DNA was studied with respect to etheno adduct and DNA strand break formation. Synthesized specific oxidized sugar products (e.g., formyl phosphate) and examined DNA damaging potential. Identification of damaged products by HPLC, EMS, LC/MS and structural elucidation by NMR.

12/95-09/97 Consultant Ministry of Energy & Environmental Affairs, Accra, Ghana Advised Ministry on major factors affecting environmental degradation and pollution in the Greater Accra Region with the goal of ensuring effective environmental management.

12/91-08/95 Postdoctoral Associate Division of Toxicology, Massachusetts Institute of Technology (M.I.T), Cambridge, MA

Developed methods for the quantification of adducts (i.e., bulky and non-bulky) in genomic DNA resulting from exposure to environmental carcinogens in humans.

Research involved synthesis and purification of 8-Hydroxy- 2-Deoxyguanosine followed by acylation with T-butoxycarbonyly-l-[35S]methionine,N-hydroxysuccinimidyl ester (35S-TBM-NHS) and separation, characterization and quantification of the acylated

products. Studies were also carried out on activation, adduction and identification of adducts of chemical carcinogens such as benzo[a]pyrene to DNA by enzymatic means under in vitro and in vivo conditions;quantification of levels of DNA and benzo[a]pyrene-DNA adducts from paraffin embedded tissues by acylation with 35 S-TBM-NHS and chracterization and identification of adducts; immunoaffinity purification of bulky and

non-bulky DNA adducts by monoclonal antibodies. Supervised research work of visiting scientists. Prepared technical reports and papers for publication and presented lectures on research.

Chemical Hygiene Coordinator – Division of BEH, M.I.T, Cambridge, MA

In charge of chemical hygiene, waste storage & accumulation, waste disposal, handling inventory of hazardous and particularly hazardous chemicals to meet OSHA and EPA standards in the Laboratory.

01/92-03/92 Summer Laboratory Training Course - M.I.T, Center for Environmental & Cancer Research, Cambridge, MA

Eukaryotic cell training laboratory dealing with micro-carrier technology. In particular, the development of forward mutation assay using human lymphocytes and fibroblasts. Other methodologies used were: polymerase chain reaction (PCR), mismatch amplification mutation assay (MAMA) and denaturation gradient gel electrophoresis (DGGE).

10/88-11/91 Research Assistant Technion - Israel Institute of Technology (IIT), Haifa, Israel

Concentrated on heavy metal toxicology in relation to fetotoxicity; toxic metals in relation to nutrient transfer, enzyme activities and hormone secretion, using young and term placentae, in a perfusion, superfusion, and incubation systems. In addition, investigated the effects of toxic metals on placental membrane fluidity, placental cholesterol, phospholipids, metallothionein, and metal accumulation in the placental membranes. Supervised the research work of several undergraduate and graduate students.

10/85-09/88 Research Assistant Technion - IIT, Haifa, Israel

Investigated in depth on how dietary supplementation with antioxidants and minerals affected the resistance of the organism to oxidative damage (i.e., hyper baric oxygen toxicity - HBO) and how these nutrients influenced glutathione (GSH) levels, a naturally occurring antioxidant, and its associated antioxidant enzymes in the GSH-redox cycle. Acquired experience in isolation and purification techniques of food proteins by precipitation, gel filtration, and affinity chromatography.

 

Teaching Experience

08/99-Date Taught undergraduate courses in General Biochemistry I (CHEM 341-01 & CHEM 341L-01) & II (CHEM 342-01 & CHEM 342L-01), Biochemical Analysis (CHEM 470-01) and Laboratory courses in Biochemistry and Biochemical analysis (CHEM 470L-01), General Chemistry (CHEM 1010 & CHEM1010L) – Tennessee State

University, Nashville, TN. Taught Graduate Advanced Biochemistry (CHEM 542-01) Tennessee State University, Nashville, TN.

Taught undergraduate and graduate courses and laboratory courses in Toxicology, Food Chemistry, Food Analysis – Israel Institute of Technology

 

Awards & Honors

2009 Faculty Development Travel Award – Tennessee State University

2007 Faculty Development Travel Award – Tennessee State University

2006 Faculty Development Award for Summer Research - Tennessee State University

2005 Faculty Development Award for Summer Research - Tennessee State University

2002 AACR-HBCU Faculty Scholar Award in Cancer Research

2002 Society of Toxicology Travel Award for Undergraduate Program for Minority Students

2001 AACR-HBCU Faculty Scholar Award in Cancer Research

2000 AACR-HBCU Faculty Scholar Award in Cancer Research

Letan Prize awarded by the Oil Foundation for Outstanding Postgraduate Thesis

Lady Davis Fellowship Trust Fund for Graduate Studies, Jerusalem, Israel

Chair, Local Section Leader – American Chemical Society

 

Professional Societies

Associate member of the American Association of Cancer Research (AACR)

American Chemical Society (ACS)

American Association for the Advancement of Science (AAAS)

American Research for Vision and Ophthalmology (ARVO)

 

Skills

Drug Interaction with DNA

Assays with several radioactive isotopes

Spectrometry (AAS, UV-VIS, EMS, LC/MS, GC/MS)

TLC, HPLC equipped with a Flow through radiomatic detector)

Multi-Step Organic Synthesis

Purification of DNA Restriction Fragments by IEC

 

Grants

1. Research Initiation, Tennessee State University ($7,000.00 - Awarded)

2. Minority Biomedical Research EARDA, TSU ($7,000.00 - Awarded)

3. The Camile & Henry Dreyfus Special Grant Award for Laboratory Improvement

for Undergraduate Instruction-Initial Inquiry Submitted for Consideration

4. George C. Marshall Space Flight Center, AL (NASA Award - $102,456) “Inspiring

Students to Excel Academically (ISEA)”. Proposal under consideration.

5. Tennessee Board of Regents ($50,000.00) “Increasing diversity among underrepresented minorities in chemistry” Proposal under consideration.

6. American Institute for Cancer Research. “Effect of genistein and quercetin on

Biomolecules and human progenitor monocytic mononuclear (U937) cells against metal

Damage" Proposal under consideration.

 

Undergraduate & Graduate Thesis Supervision, 2000 - Date

1. Tarra M. Beach, 2000/2001 Effect of sodium arsenate on the activity of alkaline phosphatase.

2. Connie Michell Hunt, 2000/2001 The influence of cadmium and nickel chloride on the activity of alkaline phosphatase: A spectrophotometric and SDS-PAGE analysis.

3. Loynecia Wilkerson, 2000 The influence of environmental nickel chloride on the activity of wheat germ acid phosphatase.

4. Spann Michelle, 2000 The Influence of zinc and calcium chloride on the activity of acid phosphatase: An in vitro study.

5. Hammond Meylinda, 2001/2002 The effect of mercuric chloride on the activity of acid phosphatase.

6. Tasfagiorges Abraham, 2002/2003 Lead chloride and its influence on the activity of alkaline phosphatase.

7. Bandele Omari, 2003/2004

8. Lacy Shareen, 2003/2004

9. Newell Tionanatasha, 2004/2005

10. Harris Shalandus, 2004/2005

11. Paula Jemes, 2005/2006

12. Mobeen Ayesha, 2005/2006

13. Lipi Saha (Graduate Student) 2005/2006

14. Maneice, Kimberly 2007/2008

15. Diona Mobley, 2008/2009

16. Hamza, Mohamed, 2008/2009

17. Overton Jazzmine, 2008/2009

18. Smith, Jennifer, 2008/2009

19. Callicutt, Jarvis, 2009/2010

20. Marcellus, St. Louis, 2009/2010

21. Green, Jaucyln, 2009/2010

22. Strong, Victoria, 2011

23. Powell, Delicia, 2011

Packard Science Instruction (PSI) Program – 2001-2004

Involved in a summer program for the mentoring of high school students and to motivate and prepare these students for college. Instructor for Chemistry component.

Science Technology Engineering Mathematics (STEM) Program – 2008

Involved in a summer program for the mentoring of high school students and to motivate and prepare these students for college.

 

Reviewer

Book review – John Wiley & Sons

Book review – Houghton Mifflin

Laboratory review – Oxford Publishing Co.

 

Departmental Committees

Currently serving on the following committees:

1. Recruitment/Outreach Committee

2. Safety Committee

3. Chair, Instrument/Technology Committee

4. Chair, Book Adoption Committee

 

University Committees

1. Committee on Research Day, 2002-2004

2. Teacher of the Year Selection Committee 2005

3. Faculty Senator for the Department of Chemistry, 2002-2004

4. Chair, Research Committee of the Faculty Senate 2003

5. University Tenure and Promotion Committee 2004

6. Member, Recruitment Committee of the COAS 2010-Date

 

Publications

Boadi, W. Y., Boadi, E. M., Harris, S., Anderson, J. B., Iyere, P. A. and Adunyah, S. E.: Lipid peroxides and glutathione status in human progenitor mononuclear (U937) cells following exposure to low doses of nickel and copper (submitted and under consideration to) J. Appl. Toxicol. 2011.

Boadi, W. Y., McCollum, G. W. and Penn, J. S.: Bioactivity and characterization of antiangiogenic vitreous proteins after penetrating ocular injury Invest. Ophthal. Vis. Sci., 47, 1761-B848, 2006.

Boadi, W. Y., Iyere, P. A. and Adunyah, S. E.: In vitro exposure to quercetin and genistein alters lipid peroxides and prevents the loss of glutathione in human progenitor mononuclear (U937) cells J. Appl. Toxicol., 25 (1), 82-88, 2005.

Iyere, P. A., Boadi, W. Y., Atwood, D. and Ross, L: Bis{(E)-6-methoxy-2-[(4-methylphenyl)iminomethyl]-phenolato}cobalt(II) Acta Cryst. E60, 304-306, 2004.

Iyere, P. A., Boadi, W. Y., Atwood, D. and Parkin, S: Supramolecular aggregation in 4,4’-bipyridin-1,1’-ium dichloride, 4,4’-bipyridin-1,1’-ium dinitrate and 4,4’-bipyridin-1-ium bromide. Acta Cryst. B59, 664-669, 2003.

Boadi, W. Y., Iyere, P. A. and Adunyah, S. E.: Effect of quercetin and genistein on copper- and iron-induced lipid peroxidation in methyl linolenate J. Appl. Toxicol. 23(5), 363-369, 2003.

Iyere, P. A., Boadi, W. Y., Brooks. R. S., Atwood, D. and Parkin, S: 4,4’-Bipyridin-1-ium bromide monohydrate. Acta Cryst. E58, 825-827, 2002.

Boadi, W. Y. and Iyere, P. A.: Kinetic and spetroscopic studies of the photochromism of bis-)mercury (II) dithizonato) nitrate (Manuscript resubmitted to Int. J. Chemical Kinetics - 2004).

Boadi, W. Y. and Dedon, P. C.: Acylation of guanine with formyl residues derived from deoxyribose oxidation. ISSX Proceedings 15, 226-227, 1999.

Jones, W.R. Boadi, W. Y. and Dedon, P. C.: New source of endogenous adducts: formation of ethenoadenine from DNA oxidation products. ISSX Proceedings 15, 224-225,1999.

Boadi, W. Y. , F. Z. Sheabar, S. Moody, D. M. Lawrence and G. N. Wogan: Quantitation of benzo[a]pyrene-DNA adducts from paraffin embedded liver tissues by the ADAM procedure. Proc. Am. Assoc. Cancer Res. 36, 112-113, 1995.

Sheabar, F. Z., S. Moody, W. Y. Boadi, D. M. Lawrence and G. N. Wogan: Benzo[a]pyrene DNA adducts from paraffin embedded tissues. Proc. Am. Assoc. Cancer Res. 35, 153-154, 1994.

Barnea, E. R., SD. A. Avigdor, W. Y. Boadi and J. H. Check: Effect of xenobiotics on quinone reductase activity in first trimester explants. Hum. Reprod. (1993), 8, 102-106.

Boadi, W. Y., J. Urbach, J. M. Brandes and S. Yannai: In vitro exposure to mercury and cadmium alter term human placental membrane fluidity. Toxicol. Appl. Pharmacol. (1992), 116, 17-23.

Boadi, W. Y., R. Shurtz-Swirski, E. R. Barnea, J. Urbach, J. M. Brandes, E. Philo and S. Yannai: Secretion of human chorionic gonadotropin in superfused young placental tissue exposed to cadmium. Arch. Toxicol. (1992), 66, 95-99.

Urbach, J., W. Y. Boadi, J. M. Brandes, H. Kerner and S. Yannai: Effect of inorganic mercury on in vitro placental nutrient transfer and oxygen consumption. Reprod. Toxicol. (1992), 6, 69-75.

Boadi, W. Y., J. Urbach, J. M. Brandes and S. Yannai: In vitro effect of mercury on enzyme activities and its accumulation in the first-trimester human placenta. Environ. Res. (1992), 57, 96-106.

Boadi, W. Y., J. Urbach, J. M. Brandes and S. Yannai: Effect of cadmium on enzyme activities in first-trimester human placentae. Toxicol. Lett. (1992), 60, 155-164.

Boadi, W. Y., R. Shurtz-Swirski, E. R. Barnea, J. Urbach, J. M. Brandes and S. Yannai: The influence of mercury on the secretion of human chorionic gonadotropin in superfused young placental tissue. Pharmacol. Toxicol. (1992), 71, 19-23.

Boadi, W. Y., J. Urbach, E. R. Barnea, J. M. Brandes and S. Yannai: Enzyme activities in the term human placenta: In vitro effect of cadmium. Pharmacol. Toxicol. (1992), 71, 209-212.

Boadi, W. Y., L. Thaire, D. Kerem and S. Yannai: Effects of dietary supplementation with vitamin E, riboflavin and selenium on central nervous system oxygen toxicity. Pharmacol. Toxicol. (1991), 68 (2), 77-82.

Boadi, W. Y., L. Thaire, D. Kerem and S. Yannai: Effects of dietary factors on antioxidant enzymes in rats exposed to hyperbaric oxygen. Vet. Hum. Toxicol. (1991), 33 (2), 105-109.

Boadi, W. Y., J. Urbach, E. R. Barnea, J. M. Brandes and S. Yannai: In vitro effect of mercury on aryl hydrocarbon hydroxylase, quinone reductase, catecholamine-O-

methyltransferase and glucose-6-phosphate dehydrogenase activities in term human placenta. Pharmacol. Toxicol. (1991), 68, 317-321.

Boadi, W. Y., S. Yannai, J. Urbach, J. M. Brandes and K. H. Summer: Transfer and accumulation of cadmium, and the level of metallothionein in perfused human placentae.

Arch. Toxicol. (1991), 65, 318-323.

Manuscripts in Preparation

Sheabar, F. Z., W. Y. Boadi, S. Moody, D. M. Lawrence and G. N. Wogan: Detection and quantification of benzo[a]pyrene DNA adducts from formalin-fixed and paraffin embedded liver tissues. (Cancer Epidemiol. Biomark. and Prevent.)

Ibim, S. E. M., K. E. Uhrich, W. Y. Boadi, R. Huang, C. T. Laurencien and R. Langer: Modulation of aryl hydrocarbon hydroxylase, quinone reductase and glucose-6-phosphate

dehydrogenase activities by poly(anhydride-co-imide) degradation products. (Toxicol. Appl. Pharmacol.).

Boadi, W. Y., F. Z. Sheabar, S. Moody, G. N. Wogan, M. L. Morningstar and D. M. Lawrence: Detection of 8-Oxo-2'deoxyguanosine, fluoranthene, benzo[a]pyrene, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) adducts by the ADAM Method.

 

Presentations

Callicutt, J., Okoro, C., and Boadi W. Y.: Synthesis and antioxidant activity of 3-(Trifluoromethyl)-3, 4-Dihydroacridin-1(2H)-one. 7th Annual TLSAMP Research Conference, Nashville, TN, November 12 – 13, 2009.

Boadi, W. Y., McCollum, G. W., Barnett J. M. and Penn J. S.: Differential gene expression in response to penetrating ocular injury. ARVO 2009 Annual Meeting, Fort Lauderdale, May 3rd - May 7th, 2009.

Lester A. H., Boadi, W. Y., McCollum, G. W. and Penn J. S.: The effect of penetrating ocular injury in angiostatic vitreous proteins. ARVO 2009 Annual Meeting, Fort Lauderdale, May 3rd - May 7th, 2009.

Boadi, W. Y., McCollum, G. W., Barnett J. M., Shah, A. S., Sharma, K. M. and Penn J. S.: The influence of age and OIR disposition on the angiostatic effect of penetrating ocular injury. ARVO 2008 Annual Meeting, Fort Lauderdale, April 27th - May 2nd, 2008.

Barnett J. M., McCollum, G. W., Jefferson, L. T., Boadi, W. Y. and Penn J. S.: The influence of penetrating ocular injury on laser-induced choroidal neovascularization in the rat. ARVO 2008 Annual Meeting, Fort Lauderdale, April 27th - May 2nd, 2008.

Maneice, K. and Boadi, W. Y.: Effect of very low doses of nickel and iron on lipid peroxidation in methyl-linolenate. 5th Chemistry Day, Tennessee State University, Nashville, TN April 27th, 2008.

Baxley, A. and Boadi, W. Y. Lipid peroxide levels in methyl linolenate following exposure to low doses of iron. 117th Meeting of the Tennessee Academy of Science, Volunteer State Community College, Gallatin, TN November 15-16, 2007.

Harris, S. and Boadi, W. Y. Nickel and copper modulates glutathione levels in U937 cells. 117th Meeting of the Tennessee Academy of Science, Volunteer State Community College, Gallatin, TN November 15-16, 2007.

Harris, S. and Boadi, W. Y. Nickel and copper modulates glutathione levels in U937 cells. 4th Chemistry Day, Tennessee State University, Nashville, TN March 22nd, 2007.

Boadi, W. Y., McCollum, G. W. and Penn J. S.: Bioactivity and characterization of antoangiogenic vitreous proteins after penetrating ocular injury. ARVO 2006 Annual Meeting, Fort Lauderdale, April 30th - May 4th, 2006.

Mobeen, A., Boadi, W. Y. and Mensah J. K.: Isolation and identification of anti-cancer constituents of Nigella sativa. 28th Annual University Wide Research Symposium, Tennessee State University, Nashville, TN March 28-30, 2006.

Jemes, P., Boadi, W. Y. and Mensah J. K.: Prospecting for novel anti-cancer agents from soil metagenome. 28th Annual University Wide Research Symposium, Tennessee State University, Nashville, TN March 28-30, 2006.

Boadi, W. Y., Clark, M. L., Helmcke, K. J., McCollum, G. W. and Penn J. S.: Antiangiogenic vitreous proteins after penetrating ocular injury. ARVO 2005 Annual Meeting, Fort Lauderdale, May 1-5, 2005.

Boadi, W. Y.: Symposium on retinal and choroidal angiogenesis. Vanderbilt University School of Medicine, Nashville, TN October 15-16, 2004.

Boadi, W. Y., Iyere, P. A., Sharpe, L. and Adunyah, S. E.: Quercetin and genistein prevent the loss of glutathione in human monocytic progenitor (U937) cells. American

Association for Cancer Research – 95th Annual Meeting, Orlando, FL March 27-31, 2004.

Newell, T. K., Henderson, B., Anderson, J., Iyere, P. A., Sharpe, L., Adunyah, S. E., Boadi W. Y.: Effect of 4,4’-bypiridin-1-ium bromide monohydrate on lipid peroxidation in human monocytic progenitor cells (U937 cells). American Chemical Society Research – 227th Annual Meeting, Anaheim, CA, March 28-April 1, 2004.

Harris, S. L. and Boadi, W. Y.: The effect of the combination of nickel and copper on glutathione levels in U937 cells. Annual Biomedical Research Conference for Minority Students (ABRCMS) – San Diego, CA October 15-18, 2003.

Boadi, W. Y., Iyere, P. A., Henderson, B., Anderson, J., Sharpe, L. and Adunyah, S. E.: Effect of 4,4’-bypiridin-1-ium bromide monohydrate on lipid peroxidation and glutathione levels in human monocytic progenitor cells (U937 cells). American Association for Cancer Research – 94th Annual Meeting, Toronto, Canada April 5-9, 2003.

Anderson, J., Henderson, B., Iyere, P. A., Sharpe, L., Adunyah, S. E. and Boadi, W. Y.: Nickel depletes glutathione levels in human monocytic leukemia U937 cells. 112th Meeting of the Tennessee Academy of Science, East Tennessee State University, Johnson City, TN November 14-15, 2002.

Henderson, B., Anderson, J., Iyere, P. A., Sharpe, L., Adunyah, S. E. and Boadi, W. Y.: Effect of copper on glutathione levels in human monocytic leukemia U937 cells. 112th Meeting of the Tennessee Academy of Science, East Tennessee State University, Johnson City, TN November 14-15, 2002.

Boadi, W. Y., Iyere, P. A. and Adunyah, S. E.: Effect of quercetin on glutathione levels in human monocytic leukemia U937 cells. American Association for Cancer Research – 93rd Annual Meeting, San Francisco, CA April 6-10, 2002.

Boadi, W. Y., Iyere, P. A. and Adunyah, S. E.: Protective effect of quercetin and genistein on iron and copper induced oxidation in human leukemia U937 cells. American

Association for Cancer Research – 92nd Annual Meeting, New Orleans, LA March 24-28, 2001.

Boadi, W. Y., and Lacy, K.: The influence of quercetin on iron-induced lipid peroxidation. 23rd Annual University Wide Research Symposium, Tennessee State University, Nashville, TN March 20-21, 2001.

Boadi, W. Y., Walton, M. D. and Mckinnon, K.: Effect of nickel chloride and cupric chloride on lipid peroxidation. 23rd Annual University Wide Research Symposium, Tennessee State University, Nashville, TN March 20-21, 2001.

Boadi, W. Y., Spann, M. and Iyere, P. A.: The influence of zinc chloride and calcium chloride on the activity of acid phosphatase: an in vitro study. 23rd Annual University

Wide Research Symposium, Tennessee State University, Nashville, TN March 20-21, 2001.

Boadi, W. Y., Beach, T. M., Hammond, M., Wilkerson, L. and Iyere, P. A.: Effect of sodium arsenate, mercuric chloride, nickel chloride on alkaline phosphatase activity. 23rd

Annual University Wide Research Symposium, Tennessee State University, Nashville, TN March 20-21, 2001.

Boadi, W. Y., Iyere, P. A. and Adunyah, S. E.: Quercetin and genistein protection against heavy metal induced damage in methyl linolenate. 23rd Annual University Wide Research Symposium, Tennessee State University, Nashville, TN March 20-21, 2001.

Boadi, W. Y., Iyere, P. A. and Adunyah, E. K.: Protective effect of quercetin and genistein on iron and copper induced oxidative methyl linolenate damage. Tennessee Academy of Science – 110th Meeting of the Tennessee Academy of Science, Belmont University, Nashville, TN November 17, 2000.

Boadi, W. Y., M. Awada, G. Laksmaiah and Dedon, P. C.: Formylated-DNA adducts from products of deoxyribose 5’-abstraction. American Chemical Society - 9th North American ISSX Meeting, Nashville, Tennessee, October 24-28, 1999.

Jones, W.R. Boadi, W. Y. and Dedon, P. C.: Formation of ethenoadenine from DNA oxidation products. American Chemical Society - 9th North American ISSX Meeting, Nashville, Tennessee, October 24-28, 1999. 

Boadi, W. Y., F. Z. Sheabar, S. Moody, D. M. Lawrence and G. N. Wogan: Quantitation of benzo[a]pyrene-DNA adducts from paraffin embedded liver tissues by the ADAM procedure. Proc. Am. Assoc. Cancer Res. 36, 112-113, 1995.

Sheabar, F. Z., S. Moody, W. Y. Boadi, D. M. Lawrence and G. N. Wogan: Benzo[a]pyrene DNA adducts from paraffin embedded tissues. Proc. Am. Assoc. Cancer Res. 35, 153-154, 1994.

Boadi, W. Y. and S. Yannai: In vitro exposure to mercury and cadmium alter term human placental membrane fluidity. 12th Trophoblast Conference, Rochester, New York, 1992.

Boadi, W. Y., S. Yannai, J. Urbach, J. M. Brandes and K. H. Summer: Metallothionein in cytosol of human placental cells exposed to cadmium. International Congress of Biochemistry, 15th Annual Meeting, Jerusalem, Israel, August 4-8, 1991.

Boadi, W. Y. : Effect of toxic metals on placental metabolism and function. Summer School for Multi disciplinary Assessment of Environmental Risks for Human Health, Siena, Italy, October 6-22, 1991.

Boadi, W. Y., J. Urbach, E. R. Barnea, J. M. Brandes and S. Yannai: Influence of cadmium on the activity of several enzymes in first-trimester human placentae. The first world Conference on Implantation and Early Pregnancy in Humans - The New Frontier, Jerusalem, Israel, November 6-8, 1991.

Boadi, W. Y., S. Yannai and D. Kerem: Cellular glutathione level increase by dietary nutrients. Proc. of the European Undersea Biomedical Society Xvth Annual Meeting, Eilat, Israel, September 17-21, 1989.

Boadi, W. Y., S. Yannai and D. Kerem: Cellular glutathione level increase by dietary nutrients: Protection against central oxygen toxicity? Proc. of the European Undersea

Biomedical Society Xvth Annual Meeting, Eilat, Israel, September 17-21, 1989, pp. 215-220.

Boadi, W. Y., S. Yannai and D. Kerem: Effect of Se-, vitamin E- and riboflavin-enriched diets on glutathione and various enzyme activities in rats exposed to hyperbaric oxygen. Federation of European biochemical Societies, 19th Annual Meeting, Rome, Italy, July 2-7, 1989.






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