Dr. Ryan Beni

Assistant Professor, Organic and Medicinal Chemistry

Beni

Assistant Professor-Organic and Medicinal Chemistry

Department of Chemistry

Contact Information:

Office: Boswell Complex Room 213

Phone: 615-963-5333

Fax: 615-963-5326

Email: rbeni@tnstate.edu

EDUCATION:

Postdoctoral Fellow    University of Rhode Island, Kingston, RI (Medicinal Chemistry; 2004-2008)

Ph.D.   Sharif University of Technology and Justus-Liebig University, Giessen, Germany (Organic Chem; 1997-2002)

M.Sc.  Sharif University of Technology (Organic Chemistry; 1995-1997)

B.Sc.   Tabriz University (Applied Chemistry; 1991-1995)

HONORS AND AWARDS:

  • Academic achievement award for individual contribution to the field in research/scholarly activity, Columbus State University, 2010.
  • Outstanding graduate of the year award for the best PhD graduate, Sharif University of Technology,2002.
  • Visiting scholar’s award, awarded by German research society "Deutsche Forschrung Gemeinschaft, DFG" for conducting research at the Justus-Liebig University, 2000.
  • Young scientist travel award, sponsored by Ministry of Science, Research and Technology for travel to Justus-Liebig University, 2000.
    • Managing editor, Sharif Journal of Chemistry, Published by department of chemistry, Sharif University of Technology, 1998-2000.
    • Research scholarship, Ministry of Science, Research and Technology for completing PhD program at Sharif University of Technology and Justus-Liebig University, 1997.

TEACHING:

  • General Chemistry
  • Organic Chemistry
  • Spectroscopic Identification of Organic Compounds (Graduate)
  • Polymer Chemistry (Graduate)
  • Biochemistry

RESEARCH INTERESTS:

  • Anticancer drug discovery and development by chemical modification
  • Synthesis and application of phosphorylated nucleosides as anti-HIV agents
  • Synthesis and evaluation of modified oligodeoxynucleotides

RECENT PUBLICATIONS (Last 5 Years):

  1. Beni, Y., Dash, C., Parang, K., Synthesis of β-triphosphotriester pronucleotides, Tet. Letters, 2015 , 56, 2247–2250.
  2. Shirazi, A., Rao, K., Tiwari, R., Oh, D., Sullivan, B., Kumar, A., Beni, Y., Parang, K., Cyclic Peptide-selenium nanoparticles as drug transporters, Molecular pharmaceutics., 2014, 11 (10) 3631-3641.
  3. Pericherla K., Shirazi, A., Rao, K., Tiwari, R., DaSilva, N., McCaffrey, K., Beni, Y., González-Sarrías, A., Seeram, N., Parang, K., Kumar, A., Synthesis and antiproliferative activities of quebecol and its analogs, Bioorg. Med. Chem. Lett., 2013, 23 (2013) 5329–5331.
  4. Dash,C., Beni, Y., Hanley, M. J., Pandhare, J., Gotte, M., Le Grice, S. F. J., Parang, K., Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside β-triphosphates, Bioorg. Med. Chem. Lett., 2011, 21, 3519–3522.
  5. Gupta, A., Mandal, D., Beni, Y., Parang, K., Bothun, G., Hydrophobicity Drives the Cellular Uptake of Short Cationic Peptide Ligands, Eur. Biophys. J., 2011, 40, 727–736.
  6. Beni, Y., Tiwari, R., Swepsonc C., Pandharec, J., Dash, C., Donceld, G. F., Parang, K., Synthesis and anti-HIV activities of bis-(cycloSaligenyl) pronucleotides derivatives of 3′-fluoro-3′-deoxythymidine and 3′-azido-3′-deoxythymidine, Tet. Letters, 2011 , 52, 802-805.
  7. Beni, Y., Dash,C., Hanley, M. J., Le Grice, S. F. J., Parang, K., Solid-Phase Synthesis of 5'-O-β,γ-Methylenetriphosphate Derivatives of Nucleosides and Evaluation of Their Inhibitory Activity Against HIV-1 Reverse Transcriptase, Tet. Letters,.2010 , 51, 3010–3013.
  8. Beni, Y., Dash,C., Hanley, M. J., Le Grice, S. F. J., Agarwal., H. K., Parang, K., Synthesis of Nucleoside 5'-O-α,β-Methylene-β-Triphosphates and evaluation of their potency towards inhibition of HIV-1 reverse transcriptase, Org. Biomol. Chem., 2010 , 8, 1271–1274.

PUBLISHED MEETING ABSTRACTS (Last 5 Years):

  1. Alnakhli, J., Boadi, W., Parang, K., Shirazi, A., Beni, Y., Triphenylmethanol conjugates of triptorelin as anti-cancer prodrugs, 250th ACS National Meeting & Exposition, Boston, MA, August 16-20, 2015, Abstract #  MEDI-225 .
  2. Alhamed, S., Beni, Y., Boadi, W., Triphenylmethanol conjugates of triptorelin as anti-lipid peroxidation agents, 250th ACS National Meeting & Exposition, Boston, MA, August 16-20, 2015, Abstract #  MEDI-226 .
  3. Beni, Y., Dabke, R., Grainger, W., Radical electropolymerization of pyrrole: Improvement of conductivity in polypyrrole homopolymers, 2014 Southeastern Regional Meeting of the ACS (SERMACS). Nashville, TN, October 16-19, 2014, Abstract # 663.
  4. Alhamed, S., Alnakhli, J., Boadi, W., Beni, Y., Design and anti-proliferative evaluation of tris(4-methoxyphenyl)methanol derivatives, 2014 Southeastern Regional Meeting of the ACS (SERMACS). Nashville, TN, October 16-19, 2014, Abstract # 707.
  5. Beni, Y., Radical electropolymerization of thiophene: Improvement of conductivity in polythiophene homopolymers, 248th ACS National Meeting & Exposition, San Francisco, CA, August 10-14, 2014, Abstract #  POLY-336 .
  6. Beni, Y., Pippas A. W., Chandravanu D., Design and anti-proliferative evaluation of cell-penetrating TPM-Dox conjugates as prodrugs, AACR Annual Meeting 2014, San Diego, CA, April 5-9, 2014, Abstract #  2512 .
  7. Beni, Y., Pippas A. W., Triphenylmethanol derivatives of triptorelin: Design and antiproliferative evaluation, 247th ACS National Meeting & Exposition, Dallas, TX, March 16-20, 2014, Abstract #  342 .
  8. Beni, Y., Parang K., Synthesis and thermal stability evaluation of six-membered cyclic triphosphates containing three nucleotides, 2013 Southeastern Regional Meeting of the ACS (SERMACS). Atlanta, GA, November 12-16, 2013, Abstract # 1150.
  9. Beni, Y., Parang K., Synthesis and anti-hiv evaluation of six-membered cyclic triphosphates containing three nucleotides, 123rd Meeting of Tennessee Academy of Science, Tullahoma, Tennessee, November 15, 2013, Abstract # CHEM CHEM 7 .
  10. Beni, Y., Robinson T., Triphenylmethanol derivatives as indicators for the acid-base volumetric titrations, 246th ACS National Meeting & Exposition, Indianapolis, IN, September 8-12, , 2013, Abstract #  135 .
  11. Beni, Y., Tiwari R., Parang K., Synthesis of tris(cycloSaligenyl) pronucleotides containing three nucleosides from 4,4',4''-methanetriyltris(2-(hydroxymethyl)phenol), 245th ACS National Meeting & Exposition, New Orleans, LA, April 7-11, , 2013, Abstract #  808 .
  12. Beni, Y., Tiwari R., Parang K., Synthesis and Anti-HIV Evaluation Of Tris(CycloSaligenyl) Pronucleotides, 122nd Meeting of Tennessee Academy of Science, Nashville, Tennessee, November 16, 2012, Abstract # CHEM 2 .
  13. Beni, Y., Love, J. M., From food antioxidants to gold nanoparticles, determination of antioxidants in natural and processed food by gold, 243rd ACS National Meeting & Exposition, San Diego, CA, March 25−29, 2012, Abstract #  228 .
  14. Beni, Y. Pippas, G., Love, J. M., Evaluation of cancer preventer foods/spices by gold nanoparticles, Georgia Academy of Science Annual Meeting, Kennesaw, Georgia., March 23 – 24, 2012, Abstract # 132 .
  15. Beni, Y., Williams T., Seeram, N., Parang K., Triphenylmethanol derivatives: synthesis and application as acid-base indicators for acid-base titrations, 63rd Southeastern Regional Meeting of the ACS (SERMACS). Richmond, VA, October 26-29, 2011, Abstract # 239.
  16. Beni, Y., Dash, C., Hanley, M. J., Le Grice, S. F. J., Agarwal, H. K., Parang, K., Structure-activity relationship studies of modified nucleoside β-triphosphates for polymerase and RNase H of HIV-1 reverse transcriptase, 43rd IUPAC World Chemistry Congress, San Juan, PR, July 30-August 7, 2011, Abstract # 592 .
  17. Beni, Y., Shirazi, A. N., Parang, K., Metal-binding properties of cyclic peptides, 43rd IUPAC World Chemistry Congress, San Juan, PR, July 30-August 7, 2011, Abstract # 594 .
  18. Beni, Y., Dash, C., Hanley, M. J., Pandhare, J., Gotte, M.,  Le Grice, S. F. J., Parang, K., Synthesis and evaluation of nucleoside β-triphosphates as multi-drug resistant HIV-1 RT inhibitors, 43rd IUPAC World Chemistry Congress, San Juan, PR, July 30-August 7, 2011, Abstract # 597 .
  19. Beni, Y., Dabke, R., Wendell G., Radical electropolymerization of pyrrole: Improvement of conductivity in polypyrrole homopolymers, 43rd IUPAC World Chemistry Congress, San Juan, PR, July 30-August 7, 2011, Abstract # 924 .
  20. Beni, Y., Love, J. M., Rugutt, J., Introducing Nanotechnology to Undergraduate Chemistry Curriculum, 42nd Middle Atlantic Regional Meeting of the American Chemical Society, College Park, MD, May 21-24, 2011, Abstract # MARM-134 .
  21. Beni, Y., Gina D. N. D., Improvement of conductivity in polythiophenes, Joint 66th Southwest and 62nd Southeast Regional Meeting of the American Chemical Society, New Orleans, LA, December 1-4, 2010, Abstract # SESW-351 .
  22. Beni, Y., Wendell C., Synthesis of modified conductivie polypyrroles, Joint 66th Southwest and 62nd Southeast Regional Meeting of the American Chemical Society, New Orleans, LA, December 1-4, 2010, Abstract # SESW-323 .
  23. Beni, Y., Tiwari R., Parang K., Synthesis of bis(cycloSaligenyl) pronucleotides containing two nucleosides from bis(methoxymethyl)benzene-1,4-diol, 240th ACS National Meeting & Exposition, Boston, MA, August 22-26, 2010, Abstract # ORGN 1075 .
  24. Beni, Y., Carrol, B., Parang K., Synthesis of lipophilic dodecyl bis(cycloSaligenyl) nucleoside monophosphate triesters, 240th ACS National Meeting & Exposition, Boston, MA, August 22-26, 2010, Abstract # ORGN 1019.
  25. Beni, Y., Parang K., Synthesis of branched lipophilic thymidine β-triphosphate triester conjugates of anti-HIV nucleosides, 240th ACS National Meeting & Exposition, Boston, MA, August 22-26, 2010, Abstract # ORGN 1020.
  26. Beni, Y., New indicators for the acid-base volumetric titrations, Georgia Academy of Science Annual Meeting, Columbus, GA, March 26 – 27, 2010, Abstract # CHEM 002.
  27. Beni, Y., Grainger, W., Improvement of conductivity in polypyrrole homopolymers, Georgia Academy of Science Annual Meeting, Columbus, GA, March 26 – 27, 2010, Abstract # CHEM 001.

 

Full CV

 

 






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