ENNESSEE STATE UNIVERSITY FALL 2003 SYLLABUS

TENNESSEE STATE UNIVERSITY FALL 2003 SYLLABUS

BIO 422-01/ BIO 422L-01 (4 credits) ENDOCRINOLOGY

Dr. Ivy TSU:Harned Hall 316, Tel. 963-7796 Meharry Medical College, Tel. 327-6585

E-mail:mivy@tnstate.edu

Office Hours: M, W 10-11a, 12n-2p; T, F 11a-12n, other times by APPOINTMENT

SYLLABUS subject to CHANGE due to discretion of instructor.

Course Description-A brief history of endocrinology and introduction to terms such as hormone, receptor and endocrine. An overall survey of the subject will involve the approach by fundamental principles, histology, regulation and function of glandular tissues. Appropriate clinical indications will be described, including experiments of ablation and replacement. Roles of both the cardiovascular and reproductive systems will be examined in relation to glandular vascularity and some instances of diffusion proximity, plus some specific details for hormone dissemination. The ideal direct parameters to establish a tissue as an endocrine organ , and a more practical way of collecting, concentrating and assaying the blood leaving a particular gland for hormonal activity. The study includes tissues such as the pituitary, thyroid, parathyroid, pancreas, adrenal, gonads, localized gastrointestinal system structures, and other appropriate organs. The aspects considered will provide for the biology student a greater understanding of hormone action at specific sites, the cellular synthesis of different types of hormones, cellular storage and mechanisms of hormone release, hormone transmission in the blood and carrier proteins, recognition and reception of hormone, and finally the direct cellular response.

Course Purpose-This course is designed for the BS biology major, premedical, predental, and health-related sciences undergraduate student to develop an understanding of the essential principles and unifying themes of endocrinology to physiology, medicine, embryology, and comprehend the physiologic processes and daily activities required for normal endocrine function in mammals, particularly humans.

Course Goals/Objectives (Competencies)-A student upon successful completion of this course should be able to:

-define various terminology related to the endocrine function

-describe the synthesis of hormones and their distinct categories correctly

-compare and contrast different hormones regarding their cellular sources and principle actions

-understand for humans the adaptive capabilities of the body associated with maintaining homeostasis

-explain the physiologic importance of the various endocrine glands and their relationships in humans

Course Audience- undergraduates classified primarily at the senior level that either have completed or are enrolled currently in upper level science courses. Prerequisites include introductory biology and chemistry, ecology, genetics, microbiology, cell biology, and other science courses. For the normal anatomy and physiology of the human body it is assumed that the student possesses the fundamental knowledge to complete the necessary reading and comprehensive aspects of this course presentation.

Course Attendance Policy-See the TSU Undergraduate Catalog Guidelines. No active cellular phones, pagers, beepers, computers etc. are permitted in the classroom during lecture, examination or quiz periods. Students are advised to attend all scheduled class periods. Absentee: Excuses for absences will ONLY be accepted if issued and appropriately signed by the office of Student Affairs or your Major Department at TSU.

Learning Resources-Required textbook: Basic & Clinical Endocrinology, 6^TH Edition (2001), F.S. Greenspan, and D.G. Gardner, (Lange Medical Books/McGraw-Hill Publishing, New York, NY). Supplemental materials may be used for course instruction. REQUIRED READING for each lecture will consist of the designated chapters in the textbook.

Instructional Methodology- Lectures, special assignments, examinations and quizzes will be either presented or distributed by the instructor. Library items will be used as supplemental materials including books, journal articles, videos, and other selected topics will also be included in the presentations for instructional purposes.

Learning Competencies- As indicated above in the Course Goals/Objectives section.

Evaluation Procedures-In assessment of the learning competency the use of examinations, quizzes and special assignments will be the basis of student evaluation. Examinations: Written exams will consist of multiple choice and essay questions. Quizzes: Fill-in the blank type of questions. It is mandatory and the student’s responsibility to notify the course instructor if he/she is absent during a scheduled examination or quiz.

Lab Health Project: Student participation is required in a biologic health-related activity assigned by the instructor worth 10% of the course grade.

Project Display Paper: The assignment for each enrolled student is to choose any ENDOCRINE PROBLEM that causes HUMAN DISEASE/DISORDER from the course topics for this semester. Each student should prepare at least ten – twelve (10-12) double spaced written pages worth 20% of the course grade. This assignment will consist of five (5) sections each worth 4% including: 1) INTRODUCTION: description of humans susceptible to disease; 2) RESULTS: pathology definition, disease symptoms; 3) DISCUSSION: human risk factors; 4) DISPLAY MEDICATION/DRUG/THERAPEUTIC (METHODS): patient therapy, diagnostic [lab procedures] (DISPLAY medication/drug); 5) REFERENCES: five (5) or more recent [2001-2003] journals cited with complete internet address site (must include TITLE, # of pages, author, date) or publication information included. Tables and figures are NOT INCLUDED in the page count for the written portion. Tables and figures can be used in the display for this assignment which is due NOVEMBER 10, 2003. Late assignments will receive an automatic (25%) REDUCTION and only be worth 15% of the course grade.

Grading Policy-For a student, the final course grade will be determined based on the following criteria:

Lecture/Lab Exams (4) – 35%

Lab Quizzes/Dissections – 5%

Lecture Special Assignments – 5%

Lab Health Project (special assignment) – 10%

Project Display Paper (special assignment) – 20%

FINAL - 25%

The FINAL will be a comprehensive examination including chapters 1-27.

The recommended grading scale (total - 100%) for this course is as follows:

100-90% A 89.9-80% B 79.9-70% C 69.9-60% D Below 60% F

In accordance with institution policy, any "students guilty of academic misconduct (CHEATING), either directly or indirectly through participation or assistance, are immediately responsible to the instructor of the class" (TSU UNDERGRADUATE CATALOG 2001-2003, p. 29). This student will be assigned a grade of "a ZERO (0) for the FINAL examination, and a grade of "F" for the course".

HELP, ADDITIONAL ASSISTANCE WITH LECTURE TOPICS, AND OFFICE HOURS ARE AVAILABLE UPON REQUEST. PLEASE ARRANGE APPOINTMENT TIMES WITH THE INSTRUCTOR.

Dr. Ivy TSU:Harned 316, Tel. 963-7796, Meharry Medical College Tel. 327-6585, E-mail:mivy@tnstate.edu

10-21 T EXAM III (Multiple choice questions, 10% of course grade) Chaps 9-14, 16

11-10 M DISPLAY PROJECT ( 10-12 double spaced pages, 20% of course grade) DUE, Special Assignment

11-18 T EXAM IV (Multiple choice questions, 10% of course grade) Chaps 15, 17-21

12-5-12 FINAL (Multiple choice questions, COMPREHENSIVE 25% of course grade) Chaps 1-27

Students that miss an exam or quiz without NOTIFYING the INSTRUCTOR will receive a grade of ZERO (0)